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Mushrooms, against the public record

Updated

Cancer, supportive and adjuvant

Reishi, antrodia, turkey tail and nine others have been tried in people for this. The register's own words for this are cancer, neoplasm, carcinoma, chemotherapy.

49 registered trials have looked at this, and 4 of them reported.


Species by species

SpeciesHow far it has gotTrialsWith a resultRandomisedCommonly taken for it
Reishi Ganoderma lucidumRepeated trials1111yes
Antrodia Taiwanofungus camphoratusRepeated trials632yes
Turkey tail Trametes versicolorRepeated trials4015yes
Shiitake Lentinula edodesRepeated trials3015yes
Maitake Grifola frondosaA first trial401yes
Royal sun agaric Agaricus subrufescensA first trial101yes
Button mushroom Agaricus bisporusBeing tested now400—
Cordyceps Cordyceps militarisBeing tested now200—
Chaga Inonotus obliquusBeing tested now100—
Lion's mane Hericium erinaceusBeing tested now100—
Oyster mushroom Pleurotus ostreatusBeing tested now100—
Zhu ling Polyporus umbellatusBeing tested now100yes
Mesima Phellinus linteusLaboratory work000yes
Poria Wolfiporia extensaLaboratory work000—

Commonly taken for cancer, supportive and adjuvant, with the work still in the laboratory rather than in people: Mesima.


The trials themselves

Every registered study that names one of these species and a condition the register files under this heading.

RegisterStudyConditionPeopleStatusResult postedDose in the protocol
NCT03310632Determine Function of Antroquinonol in Combination With SOC in First Line Metastatic Pancreatic Cancer
Antroquinonol, Antroquinonol
Pancreatic Neoplasm55Completedyes—
NCT02047344Efficacy, Safety and Pharmacokinetics Study of Antroquinonol to Treat NSCLC
Antroquinonol
Non-small Cell Lung Cancer Stage IV31Completedyes200 mg
NCT01134016Determine MTD and to Evaluate pk, Safety/Tolerability and Efficacy Profiles of Hocena® in NSCLC Subjects
Antroquinonol
Non-small Cell Lung Cancer13Completedyes450, 600 mg/day, 50 mg
NCT02486796Immediate or Delayed Naturopathic Medicine in Combination With Neo-Adjuvant Chemotherapy for Breast Cancer
Reishi mushroom extract, Coenzyme Q10
Quality of Life5Terminatedyes—
NCT02603016Efficacy Study of Clinical Nutrition to Treat Lung Neoplasms And Breast Carcinoma
GLSE compound, Maitake mushroom extract compound
Lung Neoplasms, Breast Neoplasms480Completed——
NCT06381960Clinical Study on the Prevention and Treatment of Postoperative Metastasis of Lung Cancer by Fuzheng Quxie Rec
Fuzheng Quxie Recipe, Fuzhengquye Fang Recipe simulant
one ingredient in a multi-herb preparation
Lung Cancer356Unknown—15g
NCT05840341Clinical Efficacy of QYHJ and Standard Chemotherapy in the Treatment of Advanced Pancreatic Cancer
QingyiHuaji optimized formula, Matched placebo
one ingredient in a multi-herb preparation
Pancreatic Neoplasms305Completed—8-g
NCT07524777Ganoderma Spores Modulate the Gut-Brain Axis
Sporoderm-removed Ganoderma lucidum spore powder (RGLS), Placebo
Depression, Thyroid Cancer300Completed—4g/day
NCT06429514Study on the Mechanism of Ganoderma Lucidum Spore Powder in the Treatment of Depression
Ganoderma lucidum spore powder, placebo
Depression, Thyroid Cancer298Completed—2g
NCT05229029RSYR for Fatigue Reduction in Cancer Fatigue Caused by Chemotherapy
TCM Formula, Placebo
one ingredient in a multi-herb preparation
Cancer-related Problem/Condition196Unknown—10g, 20g
NCT04519879White Button Mushroom Sup for the Reduction of PSA in Pts With Biochemically Rec or Therapy Naive Fav Risk Pro
Clinical Observation, Patient Observation
Prostate Adenocarcinoma, PSA Failure133Suspended——
NCT04914143the Effect of Broken Ganoderma Lucidum Spore Powder on Quality of Life and Immune Function in Patients With Di
broken Ganoderma lucidum spore powder, placebo
Diffuse Large B-cell Lymphoma120Unknown——
NCT06356701Tumor Nutritional Therapy in the First-line Treatment of Stage IV NSCLC
Cancer nutritional treatment regimen (Spirulina Bifidobacterium Capsul
Long-Term Effects Secondary to Cancer Therapy120Unknown——
NCT07118735AHCC® as Immune Modulator in Cancer Patients Treated With Immunotherapy
A standardized extract of cultured Lentinula edodes mycelia (AHCC®), P
Liver Cancer, Hepatocellular Carcinoma94Not yet recruiting—3 g
NCT04319874Phase II Clinical Trial Scheme of Ganoderma Lucidum Spore Powder for Postoperative Chemotherapy of Osteosarcom
Ganoderma lucidum, Chemotherapy
Osteosarcoma80Unknown—1000mg
NCT06028022Reishi Mushroom Extract for Fatigue and/or Arthralgias/Myalgias in Patients With Breast Cancer on Aromatase In
Mushroom Extract, Placebo Administration
Estrogen Receptor-Positive Breast Carcinoma80Recruiting——
NCT01287286Cancers Treated With Combination of Antrodia Cinnamomea and Chemotherapy
AC-Can, placebo
Neoplasm, Functional Gastrointestinal Disorder64Unknown——
NCT02844114Clinical Study of Ganoderma Lucidum Spore Combined With Chemotherapy
Ganoderma lucidum spore, Placebo
Carcinoma, Non-Small-Cell Lung60Unknown—300mg, 5 tablet
NCT00575926Lingzhi for Cancer Children
LingZhi capsule
Pediatric Cancers58Completed—300 mg, 6 capsule
NCT06601283Vitamin C Plus Cordyceps to Chemotherapy Related Anemia in Pancreatic Cancer
Vitmain C plus herbal medicine
one ingredient in a multi-herb preparation
Pancreatic Cancer50Recruiting—120 mg, 300 mg/day
NCT06598033Vitamin C Plus Cordyceps to Quality of Life in Patients With Terminal Stage Pancreatic Cancer
VC plus herbal medicine
one ingredient in a multi-herb preparation
Pancreatic Cancer50Recruiting—300 mg/day, 2 g/day
NCT07755553Effect of a Mushroom Extract-Containing Topical Cosmetic Formulation During Breast Radiotherapy
Mushroom extract-containing topical cosmetic formulation, Usual moistu
one ingredient in a multi-herb preparation
Radiation Dermatitis, Breast Cancer50Completed——
NCT07755553Effect of a Mushroom Extract-Containing Topical Cosmetic Formulation During Breast Radiotherapy
Mushroom extract-containing topical cosmetic formulation, Usual moistu
one ingredient in a multi-herb preparation
Radiation Dermatitis, Breast Cancer50Completed——
NCT06601283Vitamin C Plus Cordyceps to Chemotherapy Related Anemia in Pancreatic Cancer
Vitmain C plus herbal medicine
one ingredient in a multi-herb preparation
Pancreatic Cancer50Recruiting—120 mg, 300 mg/day
NCT06598033Vitamin C Plus Cordyceps to Quality of Life in Patients With Terminal Stage Pancreatic Cancer
VC plus herbal medicine
one ingredient in a multi-herb preparation
Pancreatic Cancer50Recruiting—300 mg/day, 2 g/day
NCT07755553Effect of a Mushroom Extract-Containing Topical Cosmetic Formulation During Breast Radiotherapy
Mushroom extract-containing topical cosmetic formulation, Usual moistu
one ingredient in a multi-herb preparation
Radiation Dermatitis, Breast Cancer50Completed——
NCT04821258Effect of the Nutraceutical "MICODIGEST 2.0" on the Complications After Surgery for Colorectal Cancer
MICODIGEST 2.0 supplement, Placebo supplement
Colorectal Cancer, Surgery--Complications48Completed——
NCT04821258Effect of the Nutraceutical "MICODIGEST 2.0" on the Complications After Surgery for Colorectal Cancer
MICODIGEST 2.0 supplement, Placebo supplement
Colorectal Cancer, Surgery--Complications48Completed——
NCT04821258Effect of the Nutraceutical "MICODIGEST 2.0" on the Complications After Surgery for Colorectal Cancer
MICODIGEST 2.0 supplement, Placebo supplement
Colorectal Cancer, Surgery--Complications48Completed——
NCT04821258Effect of the Nutraceutical "MICODIGEST 2.0" on the Complications After Surgery for Colorectal Cancer
MICODIGEST 2.0 supplement, Placebo supplement
Colorectal Cancer, Surgery--Complications48Completed——
NCT04821258Effect of the Nutraceutical "MICODIGEST 2.0" on the Complications After Surgery for Colorectal Cancer
MICODIGEST 2.0 supplement, Placebo supplement
Colorectal Cancer, Surgery--Complications48Completed——
NCT04821258Effect of the Nutraceutical "MICODIGEST 2.0" on the Complications After Surgery for Colorectal Cancer
MICODIGEST 2.0 supplement, Placebo supplement
Colorectal Cancer, Surgery--Complications48Completed——
NCT04821258Effect of the Nutraceutical "MICODIGEST 2.0" on the Complications After Surgery for Colorectal Cancer
MICODIGEST 2.0 supplement, Placebo supplement
Colorectal Cancer, Surgery--Complications48Completed——
NCT04821258Effect of the Nutraceutical "MICODIGEST 2.0" on the Complications After Surgery for Colorectal Cancer
MICODIGEST 2.0 supplement, Placebo supplement
Colorectal Cancer, Surgery--Complications48Completed——
NCT04821258Effect of the Nutraceutical "MICODIGEST 2.0" on the Complications After Surgery for Colorectal Cancer
MICODIGEST 2.0 supplement, Placebo supplement
Colorectal Cancer, Surgery--Complications48Completed——
NCT07241182Antrodia Cinnamomea Extract Effects on Lung Cancer Patients' Quality of Life During Chemotherapy
Antrodia cinnamomea supplement, Turmeric-Probiotic Group
Lung Cancer (Diagnosis)40Recruiting——
NCT06450873Turkey Tail Mushroom for Treating Post-Menopausal Women With HER2-Negative ER-Positive Breast Cancer Undergoin
Coriolus Versicolor Extract, Questionnaire Administration
Estrogen Receptor-Positive Breast Carcinoma, HER2-Negative B40Recruiting——
NCT00779168White Button Mushroom Extract in Treating Patients With Recurrent Prostate Cancer After Local Therapy
white button mushroom extract, flow cytometry
Prostate Cancer36Completed—4 g, 6 g
NCT04913064Effects of White Button Mushroom on Inflammation in Obese Postmenopausal Women at High Risk of Breast Cancer
Questionnaire Administration, White Button Mushroom Extract
Breast Carcinoma26Recruiting——
NCT07178093Effects of Antrodia Cinnamomea on the Hepatoma Patients After Transcatheter Hepatic Artery Chemoembolization
Antrodia cinnamomea, placebo
Hepatocellular Carcinoma, Transarterial Chemoembolization23Terminated—2 capsule
NCT01097083Coriolus Versicolor as Palliative Therapy Compared to Placebo in Patients With Child-Pugh C Unresectable Hepat
Coriolus Versicolor
Carcinoma, Therapy20Terminated——
NCT04871412The Thoracic Peri-Operative Integrative Surgical Care Evaluation Trial - Stage III
Vitamin D3 Drops, Coriolus Versicolor
Lung Cancer, Gastric Cancer20Recruiting—1.5g, 3g
NCT05763199Standardized Extract of Cultured Lentinula Edodes Mycelia (AHCC®) in Ovarian Cancer Patients on Adjuvant Chemo
AHCC, Chemotherapy
Ovarian Epithelial Carcinoma, Fallopian Tube Carcinoma20Active not recruiting——
NCT06323473Maitake for Integrative Cancer Care
Black Maitake Prothera
Cancer20Completed——
NCT00709020White Button Mushroom Extract in Preventing the Recurrence of Breast Cancer in Postmenopausal Breast Cancer Su
white button mushroom extract, flow cytometry
Breast Cancer, Cancer Survivor16Completed—5 g/day, 8 g/day
NCT00680667Clinical Trial of Trametes Versicolor in Women With Breast Cancer
Coriolus versicolor extract
Breast Cancer11Completed—3 g, 24 g
NCT03479294Real-World Study on Adjuvant Therapy Combined With Shenlingcao Oral Liquid in Patients for Stage II and IIIA N
Shenlingcao Oral Liquid
Carcinoma, Non-Small-Cell Lung, Chemotherapy, Adjuvant9Terminated——
NCT03589781Investigating the Effects of Mikei® Red Reishi Essence EX on the Immune System of Prostate Cancer Patients and
Mikei Red Reishi Essence EX, Placebo
Prostate Cancer—Withdrawn—490 mg, 3 capsule
NCT06599710The Effects of a Food Product Containing Mushroom Extracts (AndoSanTM) in Subjects With Colorectal Cancer-rela
AndoSanTM
Cancer-related Fatigue—Withdrawn——