Updated
Gut and microbiome
Turkey tail, lion's mane, reishi and cordyceps have been tried in people for this. The register's own words for this are microbiota, gut microbiome, irritable bowel, constipation, ulcerative colitis.
Eleven registered trials have looked at this, and 1 of them reported.
Species by species
| Species | How far it has got | Trials | With a result | Randomised | Commonly taken for it |
|---|---|---|---|---|---|
| Turkey tail Trametes versicolor | Repeated trials | 1 | 1 | 1 | yes |
| Royal sun agaric Agaricus subrufescens | Repeated trials | 0 | 0 | 2 | — |
| Oyster mushroom Pleurotus ostreatus | A first trial | 0 | 0 | 1 | — |
| Shiitake Lentinula edodes | A first trial | 0 | 0 | 1 | — |
| Lion's mane Hericium erinaceus | Being tested now | 3 | 0 | 0 | yes |
| Reishi Ganoderma lucidum | Being tested now | 3 | 0 | 0 | — |
| Cordyceps Cordyceps militaris | Being tested now | 1 | 0 | 0 | — |
| Birch polypore Fomitopsis betulina | Laboratory work | 0 | 0 | 0 | yes |
| Chaga Inonotus obliquus | Laboratory work | 0 | 0 | 0 | yes |
| Poria Wolfiporia extensa | Laboratory work | 0 | 0 | 0 | yes |
| Wood ear Auricularia auricula-judae | Laboratory work | 0 | 0 | 0 | yes |
Commonly taken for gut and microbiome, with the work still in the laboratory rather than in people: Birch polypore, Chaga, Poria, Wood ear.
The trials themselves
Every registered study that names one of these species and a condition the register files under this heading.
| Register | Study | Condition | People | Status | Result posted | Dose in the protocol |
|---|---|---|---|---|---|---|
| NCT01414010 | Effects of Pre-, Pro- & Anti-biotics on Gut Microbiota | Human Gut Microbiota | 32 | Completed | yes | 1,200 mg, 250 mg |
| NCT04029649 | Beta-1,3/1,6-D-Glucan Ganoderma Lucidum on Ulcerative Colitis | Ulcerative Colitis | 204 | Unknown | — | — |
| NCT00676975 | The Efficacy of Tradition Chinese Medicine in Patients With Irritable Bowel Syndrome one ingredient in a multi-herb preparation | Irritable Bowel Syndrome | 104 | Completed | — | 17g, 34g |
| NCT01496053 | Anti-inflammatory Effect of Agaricus Blazei Murill in Inflammatory Bowel Disease (IBD) one ingredient in a multi-herb preparation | Ulcerative Colitis, Crohn's Disease | 100 | Completed | — | 30 ml |
| NCT07405957 | Effects of Two Different Lion's Mane Extracts (Lions Mane Fruiting Body & Lions Mane Fruiting Body With Mycell | Healthy Adult Females, Healthy Adult Male | 87 | Completed | — | — |
| NCT07417371 | Study on the Mechanism of Pei Tu Ning Feng Tang in Alleviating Tourette Syndrome Via Functional Near-Infrared one ingredient in a multi-herb preparation | Tourette Syndrome in Children | 60 | Completed | — | 10g, 5g |
| NCT04939961 | Effects of Hericium Erinaceus on Microbiota and Cognition | Cognitive Decline, Mild | 40 | Completed | — | 6 capsule |
| NCT07715058 | Effect of Hifas Intima Oral on Vaginal Microbiota in Healthy Women | Vaginal Microbiota, Microbiota | 30 | Completed | — | 200 mg, 53.33 mg |
| NCT07755566 | Effect of Oral Papilozumib on Vaginal and Intestinal Microbiota in Human Papillomavirus (HPV)-Positive Women | Papillomavirus Infections | 21 | Completed | — | — |
| NCT07755566 | Effect of Oral Papilozumib on Vaginal and Intestinal Microbiota in Human Papillomavirus (HPV)-Positive Women | Papillomavirus Infections | 21 | Completed | — | — |
| NCT07755566 | Effect of Oral Papilozumib on Vaginal and Intestinal Microbiota in Human Papillomavirus (HPV)-Positive Women | Papillomavirus Infections | 21 | Completed | — | — |
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